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Major in Internal Medicine

  • Major in Internal Medicine
Sang-Cheol Bae is currently the Director of Hanyang University Hospital for Rheumatic Diseases, which is the leading specialized hospital in Korea as well as Asia, the Director of Section for Clinical & Genetic Epidemiology and Economics, Institute of Rheumatology, Hanyang University, Seoul, Korea, and the Director of "Clinical Research Center for Rheumatoid Arthritis" funded by Ministry for Health, Welfare and Family Affairs, Korea.

Professor Bae is a graduate of the Hanyang University where he studied medicine and gained his MD (1984) and PhD (1993). He also gained his MPH (1998) in Harvard School of Public Health, Boston, Massachusetts. He had worked as a Rheumatology Research Fellow and an Instructor in Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts (1996-1998).

Professor Bae’s major research interests include: 1. Clinical Epidemiology, 2. Clinical Trials and Innovative Treatment, 3. Clinical Economics and Outcomes Research, and 4. Translational Research ? Genetic Epidemiology & Pharmacogenetics in the field of rheumatic diseases, particularly rheumatoid arthritis and systemic lupus erythematosus. He has published over 320 articles in this area.

■ Education

1978-1984, MD, College of Medicine, Hanyang University, Seoul, Korea
1985-1988, 1991-1993: PhD (Medicine), Hanyang University, Seoul, Korea
1996-1998, MPH, School of Public Health, Harvard University, Boston, Massachusetts

■ Professional Exprience

1996-1998 Research Fellow & Instructor in Rheumatology, Brigham & Women’s Hospital, Boston, Massachusetts
1998- Director, Section for Clinical Epidemiology & Clinical Economics, Institute of Rheumatology, Hanyang University
2005- Professor in Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea
2005- Director, Hanyang University Hospital for Rheumatic Diseases
2005-2007 Advisory board member, Medical R&D committee, Prime Minister
2008- Director, Clinical Research Center for Rheumatoid Arthritis (funded by Ministry for Health, Welfare and Family Affairs)

■ Research Interest

Clinical Epidemiology, Clinical Trials and Innovative Treatment, Clinical Economics and Outcome Research, Translational Research ? Genetic Epidemiology & Pharmacogenetics

■ Selected Articles

Domestic peer-review journals : 183
International peer-review journals : 131
1. Pharmacoeconomic analysis of thiopurine methyltransferase polymorphism screening by polymerase chain reaction for treatment with azathioprine in Korea. Rheumatology 2004;43:156-163.
2. Common Dnase I polymorphism associated with autoantibody production among systemic lupus erythematosus patients. Human Molecular Genetics, 2004;13:2343-2350
3. Cross-cultural adaptation and validation of the Korean version of the EQ-5D in patients with rheumatic disease. Quality of Life Research. 2005;14:1401-1406
4. The influence of a Polymorphism at Position -857 of the Tumor Necrosis Factor α Gene with the Clinical Response to Etanercept Therapy in RA. Rheumatology 2005;44:547-552
5. Cost-Effectiveness Analysis of MTHFR Polymorphism Screening by Polymerase Chain Reaction in Korean Patients with Rheumaoid Arthritis Receving Methotrexate. J Rheumatol 2006;33:7;1266-1274
6. Association of Anti-Cyclic Citrullinated Peptide Antibody Levels With PADI4 Haplotypes in Early Rheumatoid Arthritis and With Shared Epitope Alleles in Very Late Rheumatoid Arthritis. Arthritis Rheum. 2007;56:1454-1463
7. A regulatory SNP at position -899 in CDKN1A is associated with systemic lupus erythematosus and lupus nephritis. Genes Immun. 2009;10:482-6.
8. TRAF1 Polymorphisms associated with Rheumatoid Arthritis Susceptibility in Asians and in Caucasians. Arthritis Rheum. 2009;60:2577-2584
9. Smoking increases rheumatoid arthritis susceptibility in individuals carrying the HLA-DRB1 shared epitope, regardless of rheumatoid factor or anti-cyclic citrullinated peptide antibody status. Arthritis Rheum. 2010;62:369-77.

■ Selected Books

Medicine in Life. 2003
Textbook of Clinical Pharmacology. 2006
Clinical Statistics. 2009

■ Honors and Awards

2001 Outstanding Research Award, Hanyang University
2002 Best Professor, Hanyang University
2003 International Publication Award, Hanyang University
2003, 05, 06, 07, 08 Academic award, KRA
2004, Academic award, APLAR
2004 Best Clinical Professor, Hanyang University
2006 Gi Seok-Young GSK Medical Scholar Award
2007 Best Professor, Hanyang University
2008 Distinguished Clinical Investigator Award, APLAR

■ Academic Service

Korean Association of Internal Medicine, Korean Rheumatism Association (KRA), Korean Society for Clinical Pharmacology and Therapeutics (KSCPT),
American College of Rheumatology, SLICC (Systemic Lupus International Collaborating Clinics), PRINTO (Pediatric Rheumatology International Trials
Organization), ISPOR (International Society for Pharmacoeconomics and Outcome Research), ISOPOR (International Society for Quality of Life Research)