News register
Search section
Search area
News Type
News type
Search date
Search word OR
List of related articles
Contents of related articles
No info was found
List of related articles
Contents of related articles
No info was found
View details
Information

12/07/2019 HYU News > Academics > 이달의연구자

Title

[Excellent R&D] A Step Closer to Curing Alzheimer's Disease

Professor Kim Hee-jin (Department of Medicine)

임지우

Copy URL / Share SNS

http://www.hanyang.ac.kr/surl/2sZDB

Contents
Alzheimer's disease is one of the worst fears of the elderly and their families. There are more and more cases of early onset Alzheimer's disease affecting people as young as 27, and the number of patients is increasing at an alarming speed. By 2025, the number of patients will increase to one million, and by 2035, one out of four people will have Alzheimer's disease. Despite the urgent need for a cure, Alzheimer's is one of the diseases that does not have a medication for complete recovery. However, it was with great news that recently, Professor Kim Hee-jin (Department of Medicine) demonstrated the positive possibility of curing Alzheimer's disease using the medicine BAN2401.
 
Professor Kim Hee-jin (Department of Medicine), in her recent medical test using the medicine BAN2401, saw possibilities in curing early Alzheimer's disease patients. 


Although the cause of Alzheimer's disease has not beem clearly identified, the most probable explanation is brain damage caused by the proteins called Amyloid Beta. The abnormal deposits of Amyloid Beta in the brain destroy the brain cells responsible for memory and cognitive functions. Developed by the pharmaceutical company, Eisai Co., Ltd. and the biotechnology company, Biogen Inc., BAN2401 is an experimental medicine currently under clinical trials to remove these deposits and cure this disease. It works as an antigen, clinging onto Amyloid Beta and removing them from the brain.


Kim explained that up until now, the testing of BAN2401 was mainly done on patients who have already progressed far into the disease. The results were disappointing. Patients who had the Amyloid Beta successfully removed still died from Alzheimer’s disease. Moreover, they were unable to recover from the cognitive decline caused by Alzheimer's.

In the recent test, Kim altered the test subjects. Patients at the initial stage of brain damage--who did not yet have Alzheimer but had a slight accumulation of Amyloid Beta and symptoms of short term memory loss--were tested instead. The test achieved a significant result. The patients who were given BAN2401 showed significant improvement in their cognitive ability. This result means an entirely new possibility of complete recovery and prevention for early-onset Alzheimer’s disease, activating full-fledged research on BAN2401.
 

Kim explained that the younger generations are not entirely safe from Alzheimer's disease and emphasized the importance of keeping a healthy lifestyle according to age.


“Alzheimer’s disease can even affect young students, so it is extremely important to keep a healthy lifestyle to prevent it,” explained Kim. "Until 40, sleeping at night is crucial to deposit the brain’s waste products (with recommended bedtime being 10pm). Also, watch your weight and muscle mass, and avoid drinking and smoking. After 50 years of age, keep a close eye on blood pressure, hyperlipidemia, and blood sugar. After 65, it is important to stay occupied with favorable work and remain socially active."

Kim expressed concern that students nowadays keep to a bad habit of staying up all night and are generally stressed and depressed. “I hope they take better care of themselves, both physically and mentally,” said Kim. “When I was their age, I too felt like I was too old already, becoming excessively concerned about the future and socially withdrawn. Now that I look back, I feel like if I were to be 26 again, I would be able to do anything. Remember, you are still very young. Stay happy, positive, and active.”



Lim Ji-woo        il04131@hanyang.ac.kr

Photos by Kim Ju-eun
Copy URL / Share SNS

0 Comments