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2020-02 07

[Academics]Professor Jeong Jae-gyeong Develops a Stretchable Display

On the 6th, Hanyang University announced that Professor Jeong Jae-gyeong (Department of Electric Engineering) developed a ‘stretchable transistor’ technology that can be stretched out and easily change the size. Flexible OLED that is used for foldable cell phones, which became famous as ‘foldable smartphones,’ such as the Samsung Galaxy Fold and Huawei Mate X, is expected to evolve ultimately into a stretchable display after developing as foldable and rollable displays. Following such flows, the technology that Professor Jeong’s team developed is foreseen to be largely meaningful in the display field in the future. Commonly, the flexible display uses polyimide as a breadboard so that it can be curved or rolled. However, polyimide has a drawback that it cannot be stretched since it is a hard material. To overcome the limitation, Professor Jeong’s team made a high-performance oxide transistor over polyimide film and used polyethylene that can be stretched like a rubber band as a breadboard, so that it can be stretched threefold than before and can keep its high electric performances. Also, they planned a structure with a higher duration by replacing the previous silica gate insulator with a hybrid polymer of zirconium, organic matter, and a crosslinker. Professor Jeong said, “The hybrid material and semiconductor processing concept can later be applied to rubber breadboard that can be stretched as one wants in the future. Through this, they might be used not only for the display industry but also for various industries such as tablets, clothing, and human skin.” This research is done with the support of Samsung Electronics Research Funding & Incubation Center for Future Technology’s Next Generation Material / Element Project and the Ministry of Trade, Industry, and Energy’s Element Part Industry Future Growth Basis Project. The research result is published in a world-renowned paper, 「Advanced Functional Materials (IF = 15.6)」 in January. Kim Jeong-o (Department of Information Display Engineering), taking the Ph. D. course joined as the lead author and Professor Hong Yong-taek of Seoul National University joined as a co-author. ■ Title of the Publication: Network structure modification enabled hybrid polymer dielectric film with zirconia for the stretchable transistor application ■ Authors Professor Jeong Jae-gyeong (Corresponding Author, Hanyang University) Kim Jeong-o (First Author, Hanyang University) Hong Yong-taek (Co-author, Seoul National University) ■ Research Principles It developed an oxide transistor array that can have elasticity and can keep high performance by introducing the stress-relief structure that has a different Young’s Modulus. In detail, it synthesized and developed a new hybrid polymer insulator that can keep a good dielectric property by dispersing zirconia ceramics with high permittivity to a high polymer called PVP-co-PMMA in molecular level through the introduction of a crosslink with a silanol group. Through this, it is applied to a high mobility IGTO oxide semiconductor element. With this, it proved a high-performance TFT array concept that is 300% stretchable in a -150℃ process. Global News Team Translation by: Lee Seong-chae

2020-02 06

[Academics]Hanyang University-Ground X, Publicly Opened a Blockchain Master's Course on 'Smart Contract and Decentralized Application' Lecture

Hanyang University and Ground X have announced on the 31st that they are publicly opening full lectures on the 'Smart Contract and Decentralized Application' for free, aiming for the general development of blockchain technology and human resources regarding the field. Last year, Hanyang University made an MOU (Memorandum of Understanding) joint business agreement with Ground X and opened formal master's degree lectures for the development of blockchain education and joint research. Korea's biggest company in the messenger industry, Kakao Corporation, supported the work, having the goal of creating education and joint researches that nurture future blockchain developers. The 'Smart Contract and Decentralized Application' lecture was held for a total of 15 weeks, starting from September of 2019, providing an education covering various contents, such as basic concepts and structure of blockchain, motion fundamentals of Ground X's self-developed platform Klaytn, consensus mechanism, smart contracts and more. Areas such as blockchain application training based on real-life examples, or methods to improve the UI (User Interface)·UX (User Experience) of blockchain services were also covered in the lecture. The lecture was held by the Evangelist Engineer of Ground X, Kim Woo-joong. The lecture is open to any student or developers interested in a blockchain platform and blockchain application development, which can be found at the IT technology education platform 'InfLearn' or 'Ground X Youtube Channel'. Kim Woo-joong Ground X Evangelist mentioned that "it was very memorable to give the lecture that covers not only the basic concepts of blockchain but also the experiences and business knowledge based on various scenarios that happen in the real-life business environment." He also noted that "since the whole Hanyang University lecture is opened online for free, I hope that it helps many people that are interested in Klaytn and development and operation of blockchain application." Logo of Hanyang University and Kakao's blockchain affiliate 'Ground X' Screenshot of the lecture that is open to the public on Youtube Watch lecture video of Ground X (Youtube) : Global News Team Translated by: Lee Wonyoung

2020-02 05

[Academics]Increasing Mileage of Electric Cars with a ‘Starch Battery’

On January 21st, a co-research team of Hanyang University's Department of Energy Engineering, Chonnam National University's Department of New Material Engineering, and the KIST Energy Storing Research Group announced that they have developed a silicon-based cathode which has a fourfold battery capacity than the graphite cathode that was previously used and can be charged more than 80% in five minutes. If this is applied to electric cars, the mileage can be increased more than double. Current commercialized electronic car batteries use graphite as cathode material but a disadvantage of it is that its mileage is shorter than internal combustion cars, due to small battery capacity. To develop electric cars with longer mileage, silicon that can save energy up to ten times than graphite is now highlighted as a new cathode material. However, the difficulty of silicon commercialization is that silicon rapid expansion of volume and loss of capacity, when charging and discharging are continued. Also, although many ways to enhance the safety of silicon as a cathode material are suggested, high price and complex processes are hindering silicon from replacing graphite. The co-researching team focused on cheap materials in daily lives such as water, oil, and starch to enhance the stability of silicon. They increased a carbon-silicon material by diluting starch in the water and oil in silicon and heating them. A carbon-silicon complex is made through a heating process just like frying something. Through this, the volume expansion of silicon cathode is prevented, when charging and discharging it. ▲ Carbon-Silicon Complex Synthesis Process Micelle is made of an emulsion of water, oil, starch, and surfactant and when it is repeatedly heated and carbonized, a carbon-silicon complex is formed. (Photo courtesy by KIST) The complex showed a battery capacity (1,530mAh/g) that is four times larger than the previous graphite-based cathode material (360mAh/g), and it also showed a characteristic of stabilized capacity after more than 500 times of charging, and of more than 80% charging in five minutes. This is because the carbon complex controls the volume expansion of silicon so that the stability is increased and it gained a large output due to carbon’s high conductivity and rearrangement of silicon structure. Doctor Jeong Hoon-gi of KIST who led this research showed his expectation by saying, “An easy process and great characteristics as such have a high possibility of commercialization and they will be further used in electric cars and Energy Storing System (ESS) when applied to a lithium-ion secondary battery.” This research was conducted by the support of the Ministry of Science and ICT and as a part of KIST’s main projects and climate change response development projects. The result of the research is published in the newest edition of 「Nano Letters」, an international journal of the field of nanotechnology. ▲ An imaginary image of an electric car equipping a carbon-silicon complex cathode, made by mixing and heating the silicon from eco-friendly materials, such as corn and sweet potatoes, which are mixed with oil (Photo courtesy of KIST) Global News Team Translation by: Lee Seong-chae

2020-02 03

[Academics]Professor Park Hui-Joon, Increased the Solar Battery Efficiency by Combining Compound Semiconductor and Perovskite

On the 19th, the joint research team of Professor Park Hui-Joon of Hanyang University's Department of Organic and Nano Engineering and Professor Lee Jae-Jin of Ajou University announced that they have developed a 'tandem solar cell' by combining a flexible 'Gallium-arsenic (GsAs) compound' and a 'Perovskite semiconductor.' They used the method that increases the conversion efficiency of electronic energy by using more diverse wavelength lights, laminating a semiconductor compound crystal that absorbs large wavelengths of light, over a thin film of Perovskite that absorbs short-wavelength light. The research team succeeded in creating a thin film of Perovskite with high-efficiency, by using a method of low-temperature solution processing. The tandem battery that is made through putting the film over a gallium-arsenic compound is found to have 15% higher efficiency. A possible increase in the price of the tandem solar battery has also been managed by using low-cost Perovskite, which has the function of increasing the photoconversion efficiency of the semiconductor compound. Professor Park mentioned that "the newly developed tandem solar battery is very light and flexible, which makes it useful for automobiles, drones, wearable devices, as well as the energy source for IoT (Internet of Things) sensors." The research has been conducted with the support of the Ministry of Science and ICT, the Ministry of Education, and the Fundamental Research Business by the National Research Foundation of Korea, and the result of the research was published on the cover paper of an international academic journal, 「Advanced Energy Materials」, on December 19th, 2019. Mimetic Diagram of Perovskite-Gallium·Arsenic Tandem Structure Solar Battery (Provided by National Research Foundation of Korea) Global News Team Translated by: Lee Wonyoung

2020-01 14

[Academics][Researcher of the Month] Opening a New Method to Save the Environment through Discovering a Nanocatalyst

The Department of Materials Science and Chemical Engineering is divided into 5 different sub majors, such as Nano Technology, Bio Technology, Information Technology, and Environment & Energy Technology. Overall, it deals with discovering and creating new materials, which are related to various industries throughout the world. Professor Kim Jong-ho, researching at Hanyang University NanoChemistry Lab at ERICA Campus, has recently discovered a method of substance production and functionalization during his research. Professor Kim uncovered a new method to compose a multifunctional nanocatalyst called PdO@WO₃ and the according substance. PdO@WO₃ has never been reported in the academic world and it also serves a perfect role as both a light photocatalyst and an electrocatalyst. ▲ Professor Kim Jong-ho of the Department of Materials Science and Chemical Engineering of ERICA Campus has recently discovered a method of substance production and functionalization. The material that Professor Kim has discovered is formed through the direct conversion of a PdO nanocluster that has a catalyst function and an ultrathin 2D tungsten oxide (WO₃) nanosheets. This newly found nanosheet serves as a light photocatalyst that converts light energy into chemical energy, while also effectively initiating C-C coupling reactions. PdO@WO₃ can also be used as an electrocatalyst as mentioned above. It is viewed that PdO@WO₃ can be used as a new tool to reduce environmental problems. For example, many medical supplies and medicines such as anticancer drugs go through C-C coupling reactions to be produced. This chain reaction requires a light photocatalyst action of a chemical element called palladium (Pd). The action is usually initiated by mixing palladium into a solution, which makes the material almost impossible to recover after mixing. However, when using the new method created by Professor Kim, the solution becomes a heterogeneous mixture, thus allowing the recovery of the nanomaterial that still maintains the functionality as a catalyst. Palladium is one of the rare-earth materials, known for having a higher price than gold. The ability to use this material again would drop the unit price of the medical supplies and medicines greatly. Moreover, it would also help to improve our natural environment, because the mining of such materials is one of the great factors of environmental destruction. PdO@WO₃ can also be used for creating a next-generation battery to replace the existing lithium-ion battery. The lithium-ion battery has an explosion hazard and low efficiency, which is currently used the most in electronic cars. The demand for the next-generation battery, especially the ones such as the metal-air battery is increasing more than ever. The zinc-air battery that is created through the cathode electrochemical catalyst function of PdO@WO₃ has higher energy density, with no possibility of any explosion hazard. When the zinc-air battery technology becomes commercialized, developing electric cars that can replace cars with an internal combustion engine is expected to become much easier than before. ▲ a) A mimic diagram of C-C coupling reactions conducted using PdO@WO₃ as a light photocatalyst. b) The result of Oxygen Return Reaction conducted using PdO@ WO₃ as the electrocatalyst (Provided by Professor Kim Jong-ho) The discovery of Professor Kim (Thesis title: ‘Ultrathin WO3 Nanosheets Converted from Metallic WS2 Sheets by Spontaneous Formation and Deposition of PdO Nanoclusters for Visible Light-Driven C-C Coupling Reactions') was made possible through the failure of separate research. In the beginning, PdO@WO₃ was simply a byproduct of an experiment with another purpose. However, Professor Kim did not stop after faced with the failure. Instead, he thoroughly analyzed the result and continued various experiments on the newly created material. In the end, Professor Kim redefined the byproduct as a catalyst, after establishing a new method of conversion of the material. Professor Kim stated, “I discovered a new scientific knowledge from the result of an experiment that I thought of as a failure. I also want the students of Hanyang University to not be afraid of the result and to gain new knowledge within it.” The research took a total of two long years; one that ended up with the failed result of the former experiment, the other spent on analyzing and establishing PdO@WO₃. The NanoBio Chemistry Lab of Hanyang University, where Professor Kim's research was done, has continued its studies on creating eco-friendly nanocatalyst material. Professor Kim gained the original patent on the conversion method of PdO@WO₃ and published the work on a scientific journal. He is now considering the publication of how PdO@WO₃ can be applied and used for the metal-air battery. Global News Team

2020-01 08

[Academics]Professor Shin Heung-soo’s Team Has Developed a New Stem Cell Delivery Method Inspired from Lotus

Professor Shin Heung-soo Hanyang University announced on the 7th that a team led by Shin Heung-soo, a professor at the Department of Bio Engineering, recently developed a stem cell delivery technology that can more efficiently treat a wide range of wounds caused by burns as such. Professor Shin developed a method that can produce large quantities of ‘stem cell three-dimensional spheroid’, known to be efficient in treating wounds and deliver them evenly to a wide range of areas. The technology is expected to be widely used to treat patients with extensive area wounds such as burns and ulcers when it can be commercialized in the future. Stem cells are being researched to treat various incurable diseases by injecting it into the human body since they possess functions such as self-replication, differentiation possibility into various cells, growth factors, and immunosuppression factor secretion. However, stem cells had the disadvantage of significant decrease in cell function since the environment around the cell differs from the environment in the body when incubating in vitro system and the limitation that local transmission in the human body is possible in the form of an injection, but it cannot regenerate the tissue in a wide area of damage. Professor Shin’s team derived ideas from lotus and solved these problems. He created a biomaterial that small rooms in hundreds of micrometer-scale, formed on a large scale regularly on the surface, to replicate the structure that each seed is fixed inside lotus seedpod. He formed three-dimensional spheroids by making stem cells extracted from human fat tissues to be brought together. Dealing with the process that the fixed seeds inside lotus become released outside due to external forces, he designed the stem cell spheroids formed in each room to be released externally when biological material expands. As a result of animal model testing, the three-dimensional spheroids produced through this process could be transplanted into a wide-range skin wound easily and showed a cure effect that is improved twofold. Professor Shin said, “This research can increase the survival rate of cells transplanted in the human body by refining the delivery method of stem cell treatment that a lot of people are interested in. It is a meaningful original technology to increase the efficiency of cell treatment with a small number of cells.” This work was researched together with Professor Choi Yu-seok of the University of Western Australia and Professor Moon Seong-hwan of Konkuk University College of Medicine, and the result of the research is listed on the December volume of ‘Biomaterials’, the magazine of authority in the biomaterials field. The research was funded by the Mid-sized Research Support Project and Natural Simulation Innovation Technology Development Project of National Research Foundation, Ministry of Science and ICT. ▲ A biomaterial for the stem cell spheroid delivery and production, based on the lotus-simulated biomaterial. (Left) A mimetic diagram of hydrogel that has a lot of rooms alike lotus, produced with micro-process technology (Middle) A mimetic diagram of stem cell spheroid that has a three-dimensional structure formed in each room through stem cell (Right) A process that spheroid is being delivered through external stimulation for transplantation Global News Team Translated by: Lee Seong-chae

2019-12 11

[Academics]Kim Chul-geun, professor of Life Science, discovers new anticancer drugs

▲ Professor Kim Chul-geun Kim Cheol-geun, a professor of Life Science at Hanyang University, recently developed a new approach to discover binding drugs in Intrinsically Disordered Protein Region (IDPR), according to Hanyang University on November 27. It can be used to develop new anticancer drugs that can suppress cancer metastasis. This research has a significant impact in curing cancer since cancer patients have a high mortality rate from metastatic cancer than primary cancer. The nonstructural regions of a protein function in vivo through interactions with other proteins. Particularly, since cancer cells have many proteins with the non-structural region, it has been a focal point as a drug target when developing new drugs. However, since the nonstructural protein region does not have a standardized three-dimensional structure, it has been difficult to apply the structural-based drug discovery method1). Professor Kim's team successfully discovered the new drug by focusing on the 'Disorder to Order Transition' (DOT)2)’ property of the nonstructural protein region and established a computer simulation platform that predicts and analyzes the cancer metastasis protein MBD2. Kim's findings have significant implications for the development of new drugs that target transcription factors and epigenetics that are involved in gene expression control. It also makes sense for the first time to demonstrate and demonstrate that MBD2-mediated chromatin remodeling complexes may be useful target systems in the development of cancer metastasis inhibitors. Professor Kim said, "The substances discovered in this research do not show side effects on normal cells, so they are expected to be applicable to clinical trials as cancer metastasis control agents. He also added, "If so, it could be used for research on the development of various diseases besides cancer.” The research was supported by the National Research Foundation's support for mid-sized researchers and the Ministry of Science and ICT's Bio and Medical Technology Development Project. It was published in Science Advances, a sister magazine of Science on November 20. This research has done by co-first authors, Dr. Kim Min-young, Life Science professor at Hanyang University (current postdoctoral researcher, University of Florida, USA) and Dr. Na In-seong, a professor at University of South Florida (current postdoctoral researcher, Boston Children's Hospital, Harvard Medical School, USA). Also, professor Won Hyeong-sik (Biomedical Science and Engineering, Konkuk University) and professor Vladimir Ubersky (University of South Florida) participated as corresponding authors. 1) a technology to reasonably design binding drug based on the standardized structure of the target protein 2) It might have a standardized structure when combined with other proteins Global News Team Translated by Hyejeong Park

2019-12 03

[Academics][Notice] The Medical Research Collaboration Center hosts a special lecture on 'Meta Learner and Auto A.I.'

Hanyang University's Medical Research Collaboration Center will host a third lecture series on the Artificial Intelligence Research Network. The theme is 'Meta Learner and Auto A.I.' The event will be held at 5:30 pm on December 9th at the Lim Woo-sung International Conference Hall, on the 4th floor of the Lecture Hall of the Seoul Campus. The special lecture will be presented by Cho Dong-yeon, a member of T-Brain, SK Telecom's A.I. Center. The lecture will be linked to the Paiknam meeting room at Hanyang University's Guri Hospital. Global News Team Translated by Hyejeong Park

2019-11 13

[Academics][HYU Research] Develops Self-Powered Artificial Muscle

* This article is published in 2019 Hanyang Research Magazine Vol.2 Professor Kim Seon-jeong Develops Self-Powered Artificial Muscle The development of artificial joints or skeletons is highly regarded as a technology for a healthy life, which human nature is longing for. In the midst of this, researches are actively underway to create even muscles, which are one of the largest components in human body, with the artificial technology. In 2017, professor Kim Seon-jeong of Hanyang University, Division of Electrical and Biomedical Engineering and eight teams from three countries have succeeded in developing the world's first artificial muscle energy harvester (regenerating electrical energy from an energy that is thrown away in nature). Professor Kim's research was consecutively selected for Creative Research Initiative Program, supported by Ministry of Science and ICT and National Research Foundation of Korea to foster world-class researchers in 2006 and 2015. As a result, artificial muscles with advanced materials and energy storage devices which stores an electrical energy for driving the artificial muscles have been developed and published four times in Science since 2011. The fifth article is also an extension of the ongoing research on artificial muscles. He further developed a self-powered emergency signal device (product name: Self-Powered Emergency Signal Device), which had the honor of winning the Innovation Award at 2019 CES. Professor Kim said, “From 2006 to 2015, we published numerous papers regarding to the artificial muscles as a Center for BioArtificial Muscle, and we are continuing to conduct research on electrical energy that can move the artificial muscles as a Center for Self-Powered Actuation.” also added that, “The technology of harvesting the electric energy from artificial muscle was selected for one of Korea's top 10 technologies news in 2017.” After 15 years in research, succeeding in developing artificial muscles that are more powerful than human muscles up to 40 times, he is now focusing on an energy that could actuate the artificial muscles. “As human muscles produce energy themselves to contract, artificial muscles need energy to move freely. We are studying yarn-type artificial muscles that can generate electricity while moving on their own on the basis of biomimetic engineering.” said professor Kim to introduce his research activities. According to Kim’s explanation, the generated energy from artificial muscles can not only move artificial muscles, but also replace conventional batteries. Batteries have good performance, however, they have disadvantages of discharging quickly and being useless in extreme environments such as in low temperatures or underwater. However, this yarntype harvester is not affected by these environments and expected to be utilized in various industries. Currently, the research is being conducted with professor Kim Seon-jeong, University of Texas in the United States and University of Wollongong in Australia, and they are recognized as the world’s top group in the fields. "We don’t have many researchers in the group, but they are elite. We want students to have a challenging spirit by presenting them with research interesting subjects,” said professor Kim at the end of the interview. “Teaching by rote has its limitations, so you have to be interested in, passionate and active to be effective,” said Kim to the students. Click to Read Hanyang Research 2019 Vol.2

2019-11 13

[Academics][HYU Research] Develops 5G Center into 5G/Unmanned Vehicle Research Development Center

* This article is published in 2019 Hanyang Research Magazine Vol.2 Professor Kim Sun-woo, Electronic Engineering Develops 5G Center into 5G/Unmanned Vehicle Research Development Center As South Korea succeeded in commercializing the world’s first 5G technology in early April, expectations that growth in various fields utilizing the technology are growing. Professor Kim Sun-woo (Department of Electronic Engineering) of Hanyang University is continuing his research to make this expectation a reality at the 5G/Unmanned Vehicle Convergence Technology Research Center which opened on campus in 2017. Realizing the importance of 5G technology and unmanned vehicles rather early, Hanyang University established the 5G/Unmanned Vehicle Convergence Technology Research Center in the fall of 2017 to foster the development of human resources in the areas of 5G and unmanned vehicles such as self-driving cars and drones with 4.5 billion KRW in subsidies from the Ministry of Science and ICT. Hanyang University, Seoul National University, Ajou University, and 11 companies including Contela, AM Telecom, Renault Samsung Motors, UVify, Geo Plan, Robowell Korea, InfoWorks, Funzin, Ascen Korea, and Essys will form a consortium to establish a research center. This research center is expected to be operational by 2022. The research center develops software and hardware through applied mathematics-based research. It requires global competitiveness, high-quality programming skills, and it will last up to six years. Kim said, “As well as building a solid foundation, we are conducting research in conjunction with talented researchers from around the world.” Research centers are also actively conducting research on unmanned vehicles, including self-driving cars, Smart Cities, Internet of Things, and drones. Professor Kim predicts these will all be developed and used based on 5G technology. Kim is currently working on the research on 5G technology. In the past, communication technology was used only for communicating or transmitting data, but it will be extended to communication between objects in the future. Therefore, this core technology is the basis for autonomous vehicles, IoT technologies, and drones, that are drawing attention from various unmanned vehicles. “Development of 5G and unmanned vehicle source technology and developing human force are very important nationally,” Kim said. He added, “Hanyang’s research center is playing a big role enhancing the status of the university.” In addition, he said, “We will continue to cultivate great talents for the rapidly changing telecommunications sector such as 5G and 6G in the future. We are constantly working on distinguished research programs for our students." Meanwhile, in April, Professor Kim was invited to the ICT Future Talent Forum 2019 held at COEX in Samsungdong. It featured ‘Unmanned vehicle’s cooperative positioning and autonomous driving', 'Drone cluster flight assistance object recognition demonstration', 'CHEM VR LIBRARY', ' Cinematic VR <Confession>', ' ‘Object recognition video', ' Hybrid V2X terminal', and etc. Professor Kim said, “We were able to exchange research topics and technology trends from each university's ICT research center. The exhibition allowed us to check the research conducted at the center and cultivate the researchers one step further.” Click to Read Hanyang Research 2019 Vol.2

2019-11 13

[Academics][HYU Research] Contributes to the Advent of a "Hydrogen Economy" by Significantly Reducing the Catalyst Cost

* This article is published in 2019 Hanyang Research Magazine Vol.2 Professor Song Tae-seup, Energy Engineering Contributes to the Advent of a "Hydrogen Economy" by Significantly Reducing the Catalyst Cost The Paris Climate Change Agreement signed in 2015 in Paris, which will transform not only Korea’s but the world's energy market, took up the role of transforming existing fossil fuels into alternative energy. With the recent growing interest in hydrogen, it is quickly becoming a popular energy source, even to the extent that the current government has declared a “hydrogen economy.” Song Tae-seup of the Hanyang University Department of Energy Engineering research team developed the catalyst materials with high efficiency, low cost, and high durability in line with this trend. This is expected to accelerate the revitalization of the hydrogen economy by succeeding in lowering the production cost of hydrogen. The hydrothermal technique requires a catalyst to electrolyze water to separate the hydrogen and oxygen. Catalytic materials are Metal-Metalloid elements based on transition metals, and research is being actively conducted on them. Among those elements, the development of Metal-Metalloid materials including triple and quadruple elements has continuously been attempted in order to take advantage of the varying electronic levels of the transferred metal. There was a limit to forming a stable compound with existing technology. The Metal-Metalloid materials based on transition metals alone were not stable in the electrolyte due to the dissolution of the metal element. Professor Song Tae-seup of the Department of Energy Engineering solved this issue using Atomic Layer Deposition (ADL) technology. In addition, Professor Song proposed the possibility of reducing the cost of catalyst by up to 20 percent, by developing the world’s first catalyst surface partial amorphous technology and enhancing hydrogen generation efficiency to four times that of conventional noble metal based catalysts. Professor Song said, “The hydrogen economy consists of the production, storage, and transportation of hydrogen,” and explained the need for this research by saying, “Among them, hydrogen production is an important technology for activating the hydrogen economy”. In particular, the Moon Jae-in government announced the roadmap to revitalize the hydrogen economy in January and set specific goals such as a cost of only 3,000 won per kilogram of hydrogen and a total of 6.2 million hydrogen cars by 2040. Now reducing hydrogen production costs through hydroelectric systems has become an essential challenge. Currently, there are disadvantages in commercialization due to the expensive price of Green Hydrogen which is produced through hydrolysis and photoelectrolysis and costs 9,000-10,000 won per kilogram, which is more expensive than Grey Hydrogen which costs 1500-2000 won per kilogram and comes from a refinery or gas reforming process. Professor Song rearranged atoms on the surface of the catalyst that generate hydrogen to remedy these disadvantages. The main feature is that the surface of the transition metal used as the conventional catalyst is fluorinated. As a result, the chemical activity of the catalyst surface rose, and the hydrogen production reaction became more active. Not only did the chemical activity increase, but the physical activity did as well, so the charge to decompose hydrogen in water could be supplied more efficiently. Professor Song Tae-seup said, “The newly developed atomic rearrangement technology can be applied to various high value-added next generation energy devices such as batteries, fuel cells, and supercapacitors, as well as high- efficiency hydrogen generation catalysts,” and concluded by saying that they are the core source technologies that can contribute to the creation of new growth engines for our country. Click to Read Hanyang Research 2019 Vol.2

2019-11 13

[Academics][HYU Research] Approaches Cancer Treatment through the Convergence

* This article is published in 2019 Hanyang Research Magazine Vol.2 Professor Paek Eun-ok, Computer Science Approaches Cancer Treatment through the Convergence Thanks to recent developments of cancer treatments, there has been a marked improvement in patients’ prognoses. Nonetheless, the fear that cancer strikes in people is beyond that of other diseases. In response to this, Professor Paek Eun-ok (Department of Computer Science) of Hanyang University successfully built a foundation for a treatment plan for stomach cancer, a particularly aggressive type of the disease, by applying computer science technology to biomedical research. Having already been selected as the researcher of the month in April of 2015 for her research in linking genomics and computer science, Paek holds a pioneering position in the field, also being selected as a regular member of The National Academy of Engineering of Korea last year. Notably, she was again selected as the researcher of the month in recognition of her work in drawing up measures to diagnose early stomach cancer through research on proteogenomics in February. Early onset stomach cancer, which usually develops in people in their 30s and 40s, is expected to be impacted more heavily by genetic factors than environmental factors than other cancers. It is also difficult to detect since its cancer cells are small and widely spread (diffuse type) and is known to develop metastasis. To determine the cause of stomach cancer, genes have been usually analysis. Protein analyses paired with genetic material is also necessary for more precise classification. There can be genetic level and protein level analyses for cancer diagnosis as well as determining the cause of cancer, and Paek’s integrated analysis method (Proteogenomics) complements the information available from these two analyses and enables a deeper causation analysis. In Korea and abroad, however, protein research is still in its early stages and there is a lack of related software. Paek is working with foreign researchers in the Clinical Proteomic Tumor Analysis Consortium (CPTAC) under the National Institute of Health (NIH) to study the integrated analysis method (Proteogenomics) and develop algorithms for cancer treatment. In general, tissue cell experiments begin by collecting cell tissue, but when tissue cells are exposed to air, proteins in the cells are prone to denaturation. To overcome these difficulties and to facilitate research, Paek has been collaborating with a number of experts in various fields, including biology, chemistry, and medicine, who have been collaborating in protein research at the Korea Institute of Science and Technology (KIST), Korea University and National Cancer Center for more than a decade. To produce more reliable and accurate results, cancer tissues and healthy tissues from 80 actual patients were collected and analyzed over five years. It is difficult to assert its direct usefulness since it is still a basic study. However, it is highly meaningful that the obtained results allow multiple perspectives on various types of data related to stomach cancer simultaneously. Regarding this research, Paek explained that “the same early stomach cancer patients have varied causes of the disease, thus require personalized treatments because of different genes and proteins each person has,” and that “through this research, we will establish a software foundation that will eventually lead to more than four types of personalized cancer treatments.” Paek, who is also conducting research related to pancreatic cancer, one of the worst forms of cancer, said that “we need to conduct in-depth research with a comprehensive view, not limited to small data.” She also had some advice for students: “I want you to have a researcher’s attitude to objectively look at your subjects and study a wide range of different information.” Click to Read Hanyang Research 2019 Vol.2