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2019-12 30

[Academics][Researcher of the Month] Using Drones to Understand and Find a Solution to Fine Dust

Public awareness regarding fine dust has increased rapidly in the past decade. Weather forecasts now include daily particulate matter (PM) pollution numbers, with PM 10 meaning fine dust particles less than 10 micrometers (0.001 millimeters) in diameter. Ultrafine dust particles are dust particles smaller than 2.5 micrometers. Masks have become a necessity, and a vast number of air filtration products are topping sales. The Korean government is not standing idle as to fighting this phenomenon. A recent Seoul city government policy targeting old diesel cars for their high emission levels has banned them from entering the area within Seoul’s four main gates. However, the government also funds several research projects in order to find a solution. Professor Ahn Kang-ho (Department of Mechanical Engineering, ERICA Campus) has been part of such a project that uses drones to monitor fine dust fluctuations and understand what causes them. Professor Ahn Kang-ho (Department of Mechanical Engineering, ERICA Campus) has been developing methods of monitoring fine dust for over five years. Fine dust is created either from the top down (matter broken into pieces until they become fine dust such as yellow dust from the Gobi Desert) or the bottom up (molecules become fine dust through chemical reactions caused by high temperatures or pressures such as factories, vehicles, or ships). Ahn said that fine dust is particularly harmful as tests have shown that it is extremely difficult for the human body to filter them, which stays within the lungs and accumulates. Although people associate fine dust with factories or sandstorms, it is actually created by everyday actions like cooking meat using a frypan or smoking cigarettes. “Recently, people have been interested in fine dust, but actually, this phenomenon goes as far back as the Silla Dynasty (B.C. 57-935) in Gyeongju,” said Ahn. “There was a law that prohibited cooking rice with other materials other than charcoal.” Ahn added that some countries, especially England, learned about the dangers of this miniscule dust the hard way. Known as the Great Smog of London of 1952, the disaster killed around 12,000 people, including people suspected of having died in the following months as a result of the event. Several smog appearances in Los Angeles of the United States have also highlighted the dangers of unregulated vehicle pollution since the 1940s. Pictured is the fine dust monitoring device that Ahn created. The device is able to analyze over ten elements including time, location, wind speed, humidity, gas, and carbon particles. (Photo courtesy of Ahn) Measuring fine dust is tricky as the machines used to analyze dust particles are usually as big as cabinets and cost over 10 million won. Sampling fine dust and going back to the lab was also a big obstacle to offering real-time measurements of fine dust that was usually monitored all day. Ahn built his own machine, creating a fine dust measuring device that records elements such as time, location, wind speed, humidity, gas, and carbon particles. Ahn successfully made this comprehensive measuring device lighter, which can be fitted into a drone or backpack. Spain’s Center for Strategic and International Studies (CSIC) invited Ahn to demonstrate an earlier fine dust monitoring method using balloons in both 2014 and 2016. Ahn also works with institutions in China and Mongolia. Pictured (Left) is an earlier fine dust monitoring method using air balloons deployed in Spain in 2014, and pictured (right) is a propellarized drone flying in Mongolia to test the machine in low temperatures. (Photo courtesy of Ahn) Ahn's specialized method targeting harbors flies drones to monitor ship exhaust. The experiment was conducted in Busan in 2017. (Photo courtesy of Ahn) Mobility is key to Ahn’s three dimensional fine dust measuring method. Drones carrying the device are launched into the sky surrounding a target area and slowly ascend and descend, revealing the relation between altitude, sun position, temperature and wind direction. With this method, Ahn has offered the government several fine dust monitoring methods using drones for industrial areas, roads, harbors and farms. Ahn offered the government a comprehensive report, suggesting that it monitors these areas with differing methods, including fine dust size differences between roads, creating a map that points out exhaust creating factories and the secondary changes that the fine dust particles go through, following ship routes in harbors, and mapping out farming routes and ammonia distribution. “Managing fine dust from the source is the cheapest way to solving this problem,” said Ahn. As there are no efficient methods to eliminating fine dust, Ahn said that the best way is to prevent them from being created in the first place. Fine dust will only get worse, unless governments, industries, and the public change their everyday habits that feed this poisonous cloud. Jung Myung-suk Photos by Lee Hyeon-seon

2019-12 11

[Academics]Kim Chul-geun, professor of Life Science, discovers new anticancer drugs

▲ Professor Kim Chul-geun Kim Cheol-geun, a professor of Life Science at Hanyang University, recently developed a new approach to discover binding drugs in Intrinsically Disordered Protein Region (IDPR), according to Hanyang University on November 27. It can be used to develop new anticancer drugs that can suppress cancer metastasis. This research has a significant impact in curing cancer since cancer patients have a high mortality rate from metastatic cancer than primary cancer. The nonstructural regions of a protein function in vivo through interactions with other proteins. Particularly, since cancer cells have many proteins with the non-structural region, it has been a focal point as a drug target when developing new drugs. However, since the nonstructural protein region does not have a standardized three-dimensional structure, it has been difficult to apply the structural-based drug discovery method1). Professor Kim's team successfully discovered the new drug by focusing on the 'Disorder to Order Transition' (DOT)2)’ property of the nonstructural protein region and established a computer simulation platform that predicts and analyzes the cancer metastasis protein MBD2. Kim's findings have significant implications for the development of new drugs that target transcription factors and epigenetics that are involved in gene expression control. It also makes sense for the first time to demonstrate and demonstrate that MBD2-mediated chromatin remodeling complexes may be useful target systems in the development of cancer metastasis inhibitors. Professor Kim said, "The substances discovered in this research do not show side effects on normal cells, so they are expected to be applicable to clinical trials as cancer metastasis control agents. He also added, "If so, it could be used for research on the development of various diseases besides cancer.” The research was supported by the National Research Foundation's support for mid-sized researchers and the Ministry of Science and ICT's Bio and Medical Technology Development Project. It was published in Science Advances, a sister magazine of Science on November 20. This research has done by co-first authors, Dr. Kim Min-young, Life Science professor at Hanyang University (current postdoctoral researcher, University of Florida, USA) and Dr. Na In-seong, a professor at University of South Florida (current postdoctoral researcher, Boston Children's Hospital, Harvard Medical School, USA). Also, professor Won Hyeong-sik (Biomedical Science and Engineering, Konkuk University) and professor Vladimir Ubersky (University of South Florida) participated as corresponding authors. 1) a technology to reasonably design binding drug based on the standardized structure of the target protein 2) It might have a standardized structure when combined with other proteins Global News Team Translated by Hyejeong Park

2019-12 07

[Academics][Excellent R&D] A Step Closer to Curing Alzheimer's Disease

Alzheimer's disease is one of the worst fears of the elderly and their families. There are more and more cases of early onset Alzheimer's disease affecting people as young as 27, and the number of patients is increasing at an alarming speed. By 2025, the number of patients will increase to one million, and by 2035, one out of four people will have Alzheimer's disease. Despite the urgent need for a cure, Alzheimer's is one of the diseases that does not have a medication for complete recovery. However, it was with great news that recently, Professor Kim Hee-jin (Department of Medicine) demonstrated the positive possibility of curing Alzheimer's disease using the medicine BAN2401. Professor Kim Hee-jin (Department of Medicine), in her recent medical test using the medicine BAN2401, saw possibilities in curing early Alzheimer's disease patients. Although the cause of Alzheimer's disease has not beem clearly identified, the most probable explanation is brain damage caused by the proteins called Amyloid Beta. The abnormal deposits of Amyloid Beta in the brain destroy the brain cells responsible for memory and cognitive functions. Developed by the pharmaceutical company, Eisai Co., Ltd. and the biotechnology company, Biogen Inc., BAN2401 is an experimental medicine currently under clinical trials to remove these deposits and cure this disease. It works as an antigen, clinging onto Amyloid Beta and removing them from the brain. Kim explained that up until now, the testing of BAN2401 was mainly done on patients who have already progressed far into the disease. The results were disappointing. Patients who had the Amyloid Beta successfully removed still died from Alzheimer’s disease. Moreover, they were unable to recover from the cognitive decline caused by Alzheimer's. In the recent test, Kim altered the test subjects. Patients at the initial stage of brain damage--who did not yet have Alzheimer but had a slight accumulation of Amyloid Beta and symptoms of short term memory loss--were tested instead. The test achieved a significant result. The patients who were given BAN2401 showed significant improvement in their cognitive ability. This result means an entirely new possibility of complete recovery and prevention for early-onset Alzheimer’s disease, activating full-fledged research on BAN2401. Kim explained that the younger generations are not entirely safe from Alzheimer's disease and emphasized the importance of keeping a healthy lifestyle according to age. “Alzheimer’s disease can even affect young students, so it is extremely important to keep a healthy lifestyle to prevent it,” explained Kim. "Until 40, sleeping at night is crucial to deposit the brain’s waste products (with recommended bedtime being 10pm). Also, watch your weight and muscle mass, and avoid drinking and smoking. After 50 years of age, keep a close eye on blood pressure, hyperlipidemia, and blood sugar. After 65, it is important to stay occupied with favorable work and remain socially active." Kim expressed concern that students nowadays keep to a bad habit of staying up all night and are generally stressed and depressed. “I hope they take better care of themselves, both physically and mentally,” said Kim. “When I was their age, I too felt like I was too old already, becoming excessively concerned about the future and socially withdrawn. Now that I look back, I feel like if I were to be 26 again, I would be able to do anything. Remember, you are still very young. Stay happy, positive, and active.” Lim Ji-woo Photos by Kim Ju-eun

2019-12 03

[Academics][Notice] The Medical Research Collaboration Center hosts a special lecture on 'Meta Learner and Auto A.I.'

Hanyang University's Medical Research Collaboration Center will host a third lecture series on the Artificial Intelligence Research Network. The theme is 'Meta Learner and Auto A.I.' The event will be held at 5:30 pm on December 9th at the Lim Woo-sung International Conference Hall, on the 4th floor of the Lecture Hall of the Seoul Campus. The special lecture will be presented by Cho Dong-yeon, a member of T-Brain, SK Telecom's A.I. Center. The lecture will be linked to the Paiknam meeting room at Hanyang University's Guri Hospital. Global News Team Translated by Hyejeong Park

2019-12 02

[Academics][Researcher of the Month] Power Electronics: A Way of Providing Cost-Efficient Power Supply

Smart devices have become an integral part of our lives. They operate interactively and autonomously, supporting people’s daily lives. Electricity by far provides the main source of convenience. Professor Kim Rae-young (Division of Electrical and Biomedical Engineering) has worked in the field of power electronics to support efficient energy processing. Professor Kim Rae-young (Division of Electrical and Biomedical Engineering) studies power electronics, which deals with cost-effective control and conversion of electricity. Power electronics is the study that covers the control and conversion of electric energy. “When electricity is generated, they have unregulated voltage and frequency, and, thus, are not suitable to use,” said Kim. “Power electronics deals with converting raw electric power into the regulated energy that is available to people.” Power electronics technologies are expected to serve important roles in future society. (Photo courtesy of Kim) Traditionally, the electric power grid system has been highly dependent on large-scale power plants, such as thermal or nuclear power plants, with high-capacity power transmission and distribution lines to generate and to deliver power energy for the last hundred decades. “Unfortunately, building this kind of traditional power grid system is almost impossible in the future,” said Kim. “Nobody wants to have these kinds of large-scale power plants or high-capacity power transmission and distribution lines near their home.” This is why Kim has paid special attention to microgrid technology. A microgrid is a small-scale power grid that can operate independently or collaboratively with other small power grids. “A microgrid provides a personal, local power supply and storage system with multiple and distributed power sources,” said Kim. He aims to build up the microgrid system through the 'Versatile Lego-block Smart Power Electronics Platform.' A model of a Versatile Lego-block Smart Power Electronics Platform (Photo courtesy of Kim) Kim’s platform is connecting energy sources in parallel with the capacity of the microgrid. Kim continued his explanation by citing the example of sunlight generation. “When solar farm collects energy via its panels, voltage and frequency may vary according to weather conditions,” said Kim. “By using the Lego-block platform, a microgrid can offer a homogeneous power supply by making use of other sources of energy simultaneously.” Kim expects his platform to corroborate a more cost-effective way of generating power. Kim wants to expand his research on power electronics in a more practical direction. “I am now working on the 3D space wireless power transmission system,” said Kim. “My goal is to acquire the core technology of cordless charging which shares similarity with Wi-Fi or Bluetooth technology.” Furthermore, Kim is showing progress in constructing a direct current (DC) electric power transmission system in collaboration with KEPCO (Korea Electric Power Corporation). A DC electric power transmission system is expected to improve the stability and economy of an electric power grid system, which leads to cost-efficiency. Kim is working to further his research in a more practical sense. Some people say that what has now been proven was once only imagined. Kim is contributing to the world with innovation as he seeks to provide more convenient, new, and wonderful experiences achieved through power electronics. Oh Kyu-jin Photos by Kim Ju-eun

2019-11 25

[Academics][Excellent R&D] The Institute for Knowledge Services Selected as a Pivotal Laboratory

Each year, the National Research Foundation of Korea selects the ‘pivotal’ university laboratories to support the research of national value. This year, the Institute for Knowledge Services (IKS) of ERICA Campus was given the honor of becoming a pivotal laboratory. They will receive governmental support of 200 million won annually for three years, up to six years. IKS has conducted many notable studies on services of knowledge, and their current research topic, the ‘IC-PBL Education Method for leading consultants of middle and small-sized companies in the Fourth Industrial Revolution’ aims to strengthen one of the primary fields of knowledge services -- business consulting. Specifically, the aim is to design an education method to grow competent consultants, targeting Korea’s middle and small-sized companies in the era of the Fourth Industrial Revolution. The head of IKS is Professor Hwang Seung-june (Division of Business Administration, ERICA Campus). Professor Hwang Seung-june (Division of Business Administration, ERICA Campus) and his Institute for Knowledge Services of Hanyang's ERICA Campus was recently selected by the National Research Foundation of Korea as a ‘pivotal' university research laboratory. “One of the weaknesses of Korea is in the service of knowledge,” said Hwang. “A prime example of that weakness shows in the domain of business consultation.” Hwang pointed out that there are critical limitations in Korea’s current education of business administration. Most case studies are based on large foreign companies. Moreover, education is theory-based and outdated. In order to address this problem, Hwang suggested IC-PBL as the most suitable education model. “We are implementing IC-PBL as the main class model.” IC-PBL (Industry-Coupled Problem-Based Learning) is Hanyang’s own experimentative class method which focuses on practical problem-solving exercises using real-life issues. The class will be conducted through five steps: on the first week, a company’s personnel will explain the actual problem the company is currently experiencing. Then, students will first comprehend and analyze the situation, define the problem, name the root cause, provide a solution, and implement the solution. The results will receive feedback from the company’s personnel. His proposal of such a class model is significant, not only because it addresses the problem of current Korean service of knowledge, but also because, as Hwang emphasized, there is a need to grow powerful domestic business consultants and consulting knowledge that could be implemented on Korea’s small and medium-sized companies. Also, with the Fourth Industrial Revolution, a new model of business consultation that handles big data and AI effectively is in demand. In order to achieve this, a practical analysis of on-site cases is necessary. The Institute for Knowledge Services has conducted many notable studies on services of knowledge. With their latest research, they aim to develop powerful Korean business consultants. Hwang said that starting next semester, this education model will be implemented on Management Consulting post graduate school. The fields of industries will vary each class and each semester, including food, automobile, and service companies. Students of each class will experiment with drawing their own solutions using big data or AI analysis, paving their way to becoming a competent business consultant. "Our ultimate goal is to come up with a new, practical Korean business consultant model for small and medium-sized companies, and disseminate that knowledge,” said Hwang. Lim Ji-woo Photos by Lee Hyeon-seon

2019-11 18

[Academics][Researcher of the Month] Highly Sensitive, Power Efficient H2 and H2S Gas Sensors Adoptable to Mobile Forms

Professor Choa Yong-Ho (Department of Materials Science and Chemical Engineering) has written a thesis titled, "Facile tilted sputtering process (TSP) for enhanced H2S gas response over selectively loading Pt nanoparticles on SnO2 thin films," which depicts the development of highly sensitive gas sensors that are driven by ultra low power (ULP). Having began the research with the development of gas sensors of various mechanisms through the syntheses of gas inductors in 2010, it was developed through the Fundamental R&D Program for Core Technology of Materials and the NanoMaterial Technology Development Program hosted by the Ministry of Trade, Industry and Energy, and the National Research Foundation of Korea (NRF). Around 10 patents were registered, and some portion of the technology was transferred to Gastron. Professor Choa Yong-Ho (Department of Materials Science and Chemical Engineering) anticipates the development of various gas sensors including hydrogen and hydrogen sulfide sensors to apply to real life. A typical gas sensor has a heater built in in order to increase its sensing capabilities. However, this has resulted in an increase in power consumption that has limited mobile application and the manufacturing of small sized gas sensors. The research team led by Choa developed ultra low power gas sensors driven in room temperature of 25C, which satisfies the rising need of ultra low power, as well as highly sensitive hydrogen (H2) and hydrogen sulfide (H2S) gas sensors. While the use of natural gas is increasing day by day, the current state of homes and industrial settings are increasingly prone to gas explosion and pollution. Methods such as the ability to sense gas leakage, the ability to measure and record gas concentration, the recognition of it, and the ability to control and warn of the various pollutants discharged from combustion apparatus are in dire need as of now -- since it is impossible to detect or distinguish the type of gas or the dangers that they entail through only the human sensory organs. H2S gases are generated as a by-product of a petroleum purification process or in the manufacturing processes of glue, leather, and raw fluorescent material. The gas sensor that detects hydrogen sulfide can stop the interior breathing of cells, paralyze central nerves, and show symptoms of asphyxiation, due to its strong toxicity. Therefore, H2S gas requires successive monitoring in order to achieve local industrial development and to create a safe atmosphere. The international world is responding by actively implementing regulations regarding industrial atmosphere control and pollution emissions. The following images (from left) are an integrated wireless smart sensor module, a gas detection graph, and the sensing graph on a mobile display. (Photo courtesy of Choa) In addition, the world is rapidly shifting its focus to hydrogen energy as our interest for low-pollution alternative energy is on the rise, along with the growing concern for environmental pollution and exhaustion of fossil energy. However, hydrogen has drawbacks in itself in that it goes through spontaneous combustion or explosion when combined with oxygen in the air. Until a system is developed, hydrogen fuel can only be widely used when the system promptly detects the leakage of hydrogen and prevents the outflow of it in the first place by devising a safety measure in the production, storage, and usage of hydrogen. Choa’s research team have created a chemical resistance sensor that changes according to gas concentration, as well as a thermochemistry sensor that selectively reacts to target gas to generate heat in the reaction and applies this to the sensing. The thermochemistry sensor has the benefit of minimizing power consumption thanks to its form which signals itself generating voltage. Kim Hyun-soo - Photos by Lee Hyeon-seon

2019-11 13

[Academics][HYU Research] Develops Self-Powered Artificial Muscle

* This article is published in 2019 Hanyang Research Magazine Vol.2 Professor Kim Seon-jeong Develops Self-Powered Artificial Muscle The development of artificial joints or skeletons is highly regarded as a technology for a healthy life, which human nature is longing for. In the midst of this, researches are actively underway to create even muscles, which are one of the largest components in human body, with the artificial technology. In 2017, professor Kim Seon-jeong of Hanyang University, Division of Electrical and Biomedical Engineering and eight teams from three countries have succeeded in developing the world's first artificial muscle energy harvester (regenerating electrical energy from an energy that is thrown away in nature). Professor Kim's research was consecutively selected for Creative Research Initiative Program, supported by Ministry of Science and ICT and National Research Foundation of Korea to foster world-class researchers in 2006 and 2015. As a result, artificial muscles with advanced materials and energy storage devices which stores an electrical energy for driving the artificial muscles have been developed and published four times in Science since 2011. The fifth article is also an extension of the ongoing research on artificial muscles. He further developed a self-powered emergency signal device (product name: Self-Powered Emergency Signal Device), which had the honor of winning the Innovation Award at 2019 CES. Professor Kim said, “From 2006 to 2015, we published numerous papers regarding to the artificial muscles as a Center for BioArtificial Muscle, and we are continuing to conduct research on electrical energy that can move the artificial muscles as a Center for Self-Powered Actuation.” also added that, “The technology of harvesting the electric energy from artificial muscle was selected for one of Korea's top 10 technologies news in 2017.” After 15 years in research, succeeding in developing artificial muscles that are more powerful than human muscles up to 40 times, he is now focusing on an energy that could actuate the artificial muscles. “As human muscles produce energy themselves to contract, artificial muscles need energy to move freely. We are studying yarn-type artificial muscles that can generate electricity while moving on their own on the basis of biomimetic engineering.” said professor Kim to introduce his research activities. According to Kim’s explanation, the generated energy from artificial muscles can not only move artificial muscles, but also replace conventional batteries. Batteries have good performance, however, they have disadvantages of discharging quickly and being useless in extreme environments such as in low temperatures or underwater. However, this yarntype harvester is not affected by these environments and expected to be utilized in various industries. Currently, the research is being conducted with professor Kim Seon-jeong, University of Texas in the United States and University of Wollongong in Australia, and they are recognized as the world’s top group in the fields. "We don’t have many researchers in the group, but they are elite. We want students to have a challenging spirit by presenting them with research interesting subjects,” said professor Kim at the end of the interview. “Teaching by rote has its limitations, so you have to be interested in, passionate and active to be effective,” said Kim to the students. Click to Read Hanyang Research 2019 Vol.2

2019-11 13

[Academics][HYU Research] Develops 5G Center into 5G/Unmanned Vehicle Research Development Center

* This article is published in 2019 Hanyang Research Magazine Vol.2 Professor Kim Sun-woo, Electronic Engineering Develops 5G Center into 5G/Unmanned Vehicle Research Development Center As South Korea succeeded in commercializing the world’s first 5G technology in early April, expectations that growth in various fields utilizing the technology are growing. Professor Kim Sun-woo (Department of Electronic Engineering) of Hanyang University is continuing his research to make this expectation a reality at the 5G/Unmanned Vehicle Convergence Technology Research Center which opened on campus in 2017. Realizing the importance of 5G technology and unmanned vehicles rather early, Hanyang University established the 5G/Unmanned Vehicle Convergence Technology Research Center in the fall of 2017 to foster the development of human resources in the areas of 5G and unmanned vehicles such as self-driving cars and drones with 4.5 billion KRW in subsidies from the Ministry of Science and ICT. Hanyang University, Seoul National University, Ajou University, and 11 companies including Contela, AM Telecom, Renault Samsung Motors, UVify, Geo Plan, Robowell Korea, InfoWorks, Funzin, Ascen Korea, and Essys will form a consortium to establish a research center. This research center is expected to be operational by 2022. The research center develops software and hardware through applied mathematics-based research. It requires global competitiveness, high-quality programming skills, and it will last up to six years. Kim said, “As well as building a solid foundation, we are conducting research in conjunction with talented researchers from around the world.” Research centers are also actively conducting research on unmanned vehicles, including self-driving cars, Smart Cities, Internet of Things, and drones. Professor Kim predicts these will all be developed and used based on 5G technology. Kim is currently working on the research on 5G technology. In the past, communication technology was used only for communicating or transmitting data, but it will be extended to communication between objects in the future. Therefore, this core technology is the basis for autonomous vehicles, IoT technologies, and drones, that are drawing attention from various unmanned vehicles. “Development of 5G and unmanned vehicle source technology and developing human force are very important nationally,” Kim said. He added, “Hanyang’s research center is playing a big role enhancing the status of the university.” In addition, he said, “We will continue to cultivate great talents for the rapidly changing telecommunications sector such as 5G and 6G in the future. We are constantly working on distinguished research programs for our students." Meanwhile, in April, Professor Kim was invited to the ICT Future Talent Forum 2019 held at COEX in Samsungdong. It featured ‘Unmanned vehicle’s cooperative positioning and autonomous driving', 'Drone cluster flight assistance object recognition demonstration', 'CHEM VR LIBRARY', ' Cinematic VR <Confession>', ' ‘Object recognition video', ' Hybrid V2X terminal', and etc. Professor Kim said, “We were able to exchange research topics and technology trends from each university's ICT research center. The exhibition allowed us to check the research conducted at the center and cultivate the researchers one step further.” Click to Read Hanyang Research 2019 Vol.2

2019-11 13

[Academics][HYU Research] Contributes to the Advent of a "Hydrogen Economy" by Significantly Reducing the Catalyst Cost

* This article is published in 2019 Hanyang Research Magazine Vol.2 Professor Song Tae-seup, Energy Engineering Contributes to the Advent of a "Hydrogen Economy" by Significantly Reducing the Catalyst Cost The Paris Climate Change Agreement signed in 2015 in Paris, which will transform not only Korea’s but the world's energy market, took up the role of transforming existing fossil fuels into alternative energy. With the recent growing interest in hydrogen, it is quickly becoming a popular energy source, even to the extent that the current government has declared a “hydrogen economy.” Song Tae-seup of the Hanyang University Department of Energy Engineering research team developed the catalyst materials with high efficiency, low cost, and high durability in line with this trend. This is expected to accelerate the revitalization of the hydrogen economy by succeeding in lowering the production cost of hydrogen. The hydrothermal technique requires a catalyst to electrolyze water to separate the hydrogen and oxygen. Catalytic materials are Metal-Metalloid elements based on transition metals, and research is being actively conducted on them. Among those elements, the development of Metal-Metalloid materials including triple and quadruple elements has continuously been attempted in order to take advantage of the varying electronic levels of the transferred metal. There was a limit to forming a stable compound with existing technology. The Metal-Metalloid materials based on transition metals alone were not stable in the electrolyte due to the dissolution of the metal element. Professor Song Tae-seup of the Department of Energy Engineering solved this issue using Atomic Layer Deposition (ADL) technology. In addition, Professor Song proposed the possibility of reducing the cost of catalyst by up to 20 percent, by developing the world’s first catalyst surface partial amorphous technology and enhancing hydrogen generation efficiency to four times that of conventional noble metal based catalysts. Professor Song said, “The hydrogen economy consists of the production, storage, and transportation of hydrogen,” and explained the need for this research by saying, “Among them, hydrogen production is an important technology for activating the hydrogen economy”. In particular, the Moon Jae-in government announced the roadmap to revitalize the hydrogen economy in January and set specific goals such as a cost of only 3,000 won per kilogram of hydrogen and a total of 6.2 million hydrogen cars by 2040. Now reducing hydrogen production costs through hydroelectric systems has become an essential challenge. Currently, there are disadvantages in commercialization due to the expensive price of Green Hydrogen which is produced through hydrolysis and photoelectrolysis and costs 9,000-10,000 won per kilogram, which is more expensive than Grey Hydrogen which costs 1500-2000 won per kilogram and comes from a refinery or gas reforming process. Professor Song rearranged atoms on the surface of the catalyst that generate hydrogen to remedy these disadvantages. The main feature is that the surface of the transition metal used as the conventional catalyst is fluorinated. As a result, the chemical activity of the catalyst surface rose, and the hydrogen production reaction became more active. Not only did the chemical activity increase, but the physical activity did as well, so the charge to decompose hydrogen in water could be supplied more efficiently. Professor Song Tae-seup said, “The newly developed atomic rearrangement technology can be applied to various high value-added next generation energy devices such as batteries, fuel cells, and supercapacitors, as well as high- efficiency hydrogen generation catalysts,” and concluded by saying that they are the core source technologies that can contribute to the creation of new growth engines for our country. Click to Read Hanyang Research 2019 Vol.2

2019-11 13

[Academics][HYU Research] Approaches Cancer Treatment through the Convergence

* This article is published in 2019 Hanyang Research Magazine Vol.2 Professor Paek Eun-ok, Computer Science Approaches Cancer Treatment through the Convergence Thanks to recent developments of cancer treatments, there has been a marked improvement in patients’ prognoses. Nonetheless, the fear that cancer strikes in people is beyond that of other diseases. In response to this, Professor Paek Eun-ok (Department of Computer Science) of Hanyang University successfully built a foundation for a treatment plan for stomach cancer, a particularly aggressive type of the disease, by applying computer science technology to biomedical research. Having already been selected as the researcher of the month in April of 2015 for her research in linking genomics and computer science, Paek holds a pioneering position in the field, also being selected as a regular member of The National Academy of Engineering of Korea last year. Notably, she was again selected as the researcher of the month in recognition of her work in drawing up measures to diagnose early stomach cancer through research on proteogenomics in February. Early onset stomach cancer, which usually develops in people in their 30s and 40s, is expected to be impacted more heavily by genetic factors than environmental factors than other cancers. It is also difficult to detect since its cancer cells are small and widely spread (diffuse type) and is known to develop metastasis. To determine the cause of stomach cancer, genes have been usually analysis. Protein analyses paired with genetic material is also necessary for more precise classification. There can be genetic level and protein level analyses for cancer diagnosis as well as determining the cause of cancer, and Paek’s integrated analysis method (Proteogenomics) complements the information available from these two analyses and enables a deeper causation analysis. In Korea and abroad, however, protein research is still in its early stages and there is a lack of related software. Paek is working with foreign researchers in the Clinical Proteomic Tumor Analysis Consortium (CPTAC) under the National Institute of Health (NIH) to study the integrated analysis method (Proteogenomics) and develop algorithms for cancer treatment. In general, tissue cell experiments begin by collecting cell tissue, but when tissue cells are exposed to air, proteins in the cells are prone to denaturation. To overcome these difficulties and to facilitate research, Paek has been collaborating with a number of experts in various fields, including biology, chemistry, and medicine, who have been collaborating in protein research at the Korea Institute of Science and Technology (KIST), Korea University and National Cancer Center for more than a decade. To produce more reliable and accurate results, cancer tissues and healthy tissues from 80 actual patients were collected and analyzed over five years. It is difficult to assert its direct usefulness since it is still a basic study. However, it is highly meaningful that the obtained results allow multiple perspectives on various types of data related to stomach cancer simultaneously. Regarding this research, Paek explained that “the same early stomach cancer patients have varied causes of the disease, thus require personalized treatments because of different genes and proteins each person has,” and that “through this research, we will establish a software foundation that will eventually lead to more than four types of personalized cancer treatments.” Paek, who is also conducting research related to pancreatic cancer, one of the worst forms of cancer, said that “we need to conduct in-depth research with a comprehensive view, not limited to small data.” She also had some advice for students: “I want you to have a researcher’s attitude to objectively look at your subjects and study a wide range of different information.” Click to Read Hanyang Research 2019 Vol.2

2019-11 09

[Academics][HYU Research] The Era of Sustainable Bioenergy Is Coming

* This article is published in 2019 Hanyang Research Magazine Vol.2 Professor Jeon Byong-hun, Earth Resources and Environmental Engineering The Era of Sustainable Bioenergy Is Coming The current climate crisis from the rapid increase in carbon emissions of modern society is recognized as a planet-wide problem that exceeds regional and national boundaries, and the global interest in the production of carbon-neutral renewable energy "from the various" sources such as wind, sunlight, and tide has been raised more than ever before. Meanwhile, research on biomass-based renewable energy has also been actively conducted in recent years. Prof. Jeon Byong-Hun (Department of Earth Resources and Environmental Engineering at Hanyang University) is a renowned expert in the international bioenergy research society. Prof. Jeon’s pioneering works have been primarily on biogas production by anaerobic co-digestion using various biomass sources such as FOG (Fat, oil and grease), and on liquid biofuels production from microalgal biomass to address the solution toward the global warming. Prof. Jeon stated that, “As marine dumping of organic wastes (e.g. sewage sludge, livestock manure and food waste) has been prohibited, careful attention in their alternative treatments was emphasized for simultaneous recovery of renewable bioenergy during the treatment process of biomass.” The conventional ways of treating organic waste biomass (e.g. incineration, landfill or compost) are limited in their energy recovery and usage. However, utilizing different wastes including FOG in anaerobic digestion can lead to high yield of methane as clean renewable energy while reducing the volume of organic waste. Furthermore, unlike other types of renewable energy, biofuels can not only be utilized for the production of electricity but also directly used for combustion in engines. A researcher in Jeon’s laboratory said “The anaerobic digestion research had been somewhat difficult due to the sanitary issues related to sampling and handling of sludges produced from domestic wastewater treatment process that is used for research, plus the biological complexity and sensitivity of the anaerobic microbes in them. But I find it worthwhile to conduct the research using difficult-to-treat organic wastes that contain number of organic wastes to produce useful renewable energy.” In the concluding remarks, Prof. Jeon said, “I have obtained B.S., M.S. & Ph.D. degrees from Hanyang University, and Pennsylvania State University, USA, in natural resources and environmental engineering so I have been participating in the converged research studies, and I wanted to solve social problems such as global warming through my research. I also wish that more people and the government will get to have more interest on the societal importance of renewable energy in the future and pay their attention on the commercialization of bioenergy production from various biomass.” Click to Read Hanyang Research 2019 Vol.2